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INTRODUCTION

LYRICA 150MG CAPSULE contains Pregabalin which belongs to the group of medicines called Anticonvulsants. It is used in adults to treat neuropathic pain. Neuropathic pain (also known as nerve pain) is a long-lasting pain caused due to damage of nerves fibers present in the body. It is characterized by hot, burning, sharp, shooting, throbbing or stabbing pain sensations with tingling or numbness of body parts. It may also cause mood changes, sleep disturbances and tiredness if nerve fibers supplying the brain are damaged.

LYRICA 150MG CAPSULE can also be used to treat certain forms of epilepsy (fits or seizures) when used in combination with other anti-epileptic medicines. It may also be effective in treating generalized anxiety disorders (severe anxiety that affects daily activities) when other medicines are not effective.

Pregabalin controls seizure (fits) by reducing the abnormal activity of the nerve cells in the brain. It also reduces the pain by blocking the transmission of pain signals across the nervous system. It relieves anxiety by reducing the release of certain brain chemicals that causes abnormal mood stimulation and anxiety.

Before taking LYRICA 150MG CAPSULE inform your doctor if you have or had any lung, liver, kidney or heart problems. You must also inform your doctor before taking LYRICA 150MG CAPSULE if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse.

Avoid consuming alcohol while taking LYRICA 150MG CAPSULE as it may make you feel dizzier which can eventually lead to increased risk of injuries, falls or accidents. Do not take LYRICA 150MG CAPSULE if you are pregnant or breastfeeding without consulting your doctor. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE.

LYRICA 150MG CAPSULE should be used with extreme caution in elderly patients (aged above 65 years) particularly in those who have kidney problems. LYRICA 150MG CAPSULE may alter your blood sugar levels, therefore regularly check your blood sugar levels as a precaution. It may also cause weight gain in patients, particularly in those who are diabetic. If it bothers you, consult your doctor for advice.

Other most common side effects of taking LYRICA 150MG CAPSULE are dizziness, drowsiness, headache, dry mouth, blurred vision and swelling of body parts. Contact your doctor if any of these side effect worsens. Also, inform your doctor immediately if you experience extreme sadness with thought of harming or killing yourself (suicidal thoughts).

USES OF LYRICA 150MG CAPSULE

It is used in adults to treat:

  • Peripheral and central neuropathic pain
  • Epilepsy (fits or seizure) in combination with other medicines
  • Generalized Anxiety Disorder

HOW LYRICA 150MG CAPSULE WORKS

LYRICA 150MG CAPSULE controls seizures by reducing the abnormal activity of the nerve cells in the brain. It acts as a specific analgesic for peripheral and central neuropathic pain by blocking the transmission of pain signals across the nervous system. It relieves anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.

DIRECTIONS FOR USE

Take LYRICA 150MG CAPSULE as advised by your physician. Swallow LYRICA 150MG CAPSULE with a glass of water. Do not crush or chew the medicine. LYRICA 150MG CAPSULE can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking LYRICA 150MG CAPSULE without consulting your doctor.

SIDE EFFECTS OF LYRICA 150MG CAPSULE

COMMON

  • dizziness, drowsiness, headache
  • increased appetite
  • increased mood, confusion, disorientation, irritability
  • lack of attention, clumsiness, memory impairment
  • tremor, difficulty in speaking
  • tingling or numbness, sedation, lethargy
  • difficulty in sleeping, tiredness
  • blurred vision, double vision
  • spinning sensation, problems with balance
  • dry mouth, constipation, vomiting, flatulence, diarrhoea, nausea, swelling in abdomen
  • swelling of the extremities (such as hands, legs or fingers)
  • feeling drunk, abnormal style of walking
  • weight gain
  • muscle cramps, joint or back pain, pain in limbs
  • sore throat
  • difficulties with erection, decreased sexual drive, delayed ejaculation

UNCOMMON

  • loss of appetite, weight loss
  • high or low blood sugar
  • hallucinations, mood changes
  • dry eyes, eye pain, watery eyes, eye swelling
  • heart rate disturbances, high or low blood pressure
  • flushing
  • difficulty in breathing, dry nose, nasal congestion
  • increased salivation, heartburn, numbness around mouth
  • sweating, rash, chills, fever
  • breast pain
  • difficult or painful urination
  • allergic reaction (swollen face, itchiness, hives, runny nose, nose bleeding)
  • painful menstruation
  • cold hands and feet

RARE

  • abnormal sense of smell
  • cold sweat, tightness of the throat, swelling of tongue
  • inflammation of the pancreas
  • difficulty with writing properly
  • fluid in the lungs
  • muscle damage
  • discharge from breasts, abnormal growth of breast in men
  • low urine output
  • signs of Parkinsonism (muscle stiffness, shaking and decreased ability to move)

Stop taking LYRICA 150MG CAPSULE and consult your doctor immediately if you experience any of the following side effects:

  • serious skin reaction involving reddish non-elevated, target-like or circular patches on the trunk, often with central blisters, skin peeling, ulcers of mouth, throat, nose, genitals and eyes (Stevens-Johnson syndrome, toxic epidermal necrolysis)
  • yellow discoloration of the skin and whites of the eyes
  • suicidal thoughts

HOW TO MANAGE SIDE EFFECTS

Constipation

Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.

Dizziness Or Drowsiness

Try to rest and relax. Get enough sleep. Avoid driving or operating any heavy tools or machines completely while you are feeling dizzy or drowsy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.

Headache

Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.

Nausea And Vomiting

Take LYRICA 150MG CAPSULE with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.

WARNING & PRECAUTIONS

PREGNANCY
Contraindicated

LYRICA 150MG CAPSULE is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of childbearing age must use a suitable contraceptive method (non-hormonal methods) to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE.

BREASTFEEDING
Contraindicated

LYRICA 150MG CAPSULE is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking LYRICA 150MG CAPSULE.

ALCOHOL
Consult your doctor

Avoid consumption of alcohol while taking LYRICA 150MG CAPSULE as it could increase your dizziness.

KIDNEY
Use with Caution

LYRICA 150MG CAPSULE should be used with caution in patients with kidney diseases (such as decreased urination). Therefore, consult your doctor before taking it.

LIVER
Use with Caution

LYRICA 150MG CAPSULE should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.

ALLERGY
Contraindicated

Do not take LYRICA 150MG CAPSULE if you are allergic to the Pregabalin.

LUNGS
Use with Caution

LYRICA 150MG CAPSULE should be used with caution in patients having respiratory problems. Therefore, consult your doctor before taking it.

HEART DISEASE
Use with Caution

LYRICA 150MG CAPSULE should be used with caution in patients who have a history of heart disease (Ex. high or low blood pressure). Therefore, consult your doctor before taking it.

OTHERS

Before taking LYRICA 150MG CAPSULE, inform your doctor if you:

  • have or had constipation
  • have a history of drug abuse

Use in Pediatrics:

LYRICA 150MG CAPSULE is generally not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor before taking it.

Use in Geriatrics:

LYRICA 150MG CAPSULE should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.

INTERACTIONS

A. Drug – Drug interactions:

Before taking LYRICA 150MG CAPSULE, inform your doctor if you are taking any of the following medicines such as:

  • oxycodone (used as a pain killer)
  • lorazepam (used for reducing anxiety)
  • oral contraceptives (birth control pills) Ex. ethinyl estradiol

Overdosage:

If you or anyone else accidentally took more LYRICA 150MG CAPSULE, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include feeling sleepy, confused, agitated or restless and fits.

SYNOPSIS

Drug :   Pregabalin
Pharmacological Category :   GABA analogs
Therapeutic Indication :   Neuropathic pain, Epilepsy, Generalised Anxiety Disorders         
Dosage Forms :   Tablet, Capsule, Injection, Suspension

MORE INFORMATION

  • Keep LYRICA 150MG CAPSULE out of reach of children
  • Store LYRICA 150MG CAPSULE at room temperature

FAQs ABOUT LYRICA 150MG CAPSULE

Q: What is LYRICA 150MG CAPSULE used for?

A: LYRICA 150MG CAPSULE is an anticonvulsant drug with pain relieving properties. It is used in adults to treat neuropathic pain, certain forms of epilepsy (fits) and generalized anxiety disorders.

Q: What if I forget to take a dose of LYRICA 150MG CAPSULE?

A: If your forgot to take a dose of LYRICA 150MG CAPSULE, take it as soon as you remember. However, if it is time to take the next dose of LYRICA 150MG CAPSULE, skip the missed one and take the next dose at regular times. Do not take a double dose of LYRICA 150MG CAPSULE to compensate the missed dose.

Q: How long will it take for LYRICA 150MG CAPSULE to reduce nerve pain?

A: The time taken for LYRICA 150MG CAPSULE in treating your condition may vary from person-to-person depending upon the severity of the disease. But you may start noticing a difference from your condition after 2 weeks of using LYRICA 150MG CAPSULE. However, it may take several weeks for you to experience complete pain relief. Therefore, take LYRICA 150MG CAPSULE consistently as advised by your doctor. Do not skip doses or discontinue the therapy in the mid-way without consulting your doctor.

What happens if I stop taking LYRICA 150MG CAPSULE suddenly?

Do not stop taking LYRICA 150MG CAPSULE without consulting your doctor as it may precipitate unpleasant withdrawal symptoms (such as headache, difficulty in sleeping, nausea, anxiety, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating and dizziness). If you wish to stop LYRICA 150MG CAPSULE, talk to your doctor. Your doctor will gradually your daily dose of pregabalin and before complete cessation of therapy.

Q: Will taking a higher dose of LYRICA 150MG CAPSULE be more effective?

A: No. Do not take a higher dose of LYRICA 150MG CAPSULE than the prescribed one without consulting your doctor. Taking a higher dose of LYRICA 150MG CAPSULE may not be beneficial. Instead, it may cause serious side effects. If the prescribed dose is not effective for you, consult your doctor. Your doctor would prescribe a suitable higher dose for you or suggest an alternative therapy after evaluating your disease condition.

Q: Does LYRICA 150MG CAPSULE help with anxiety?

A: Yes. LYRICA 150MG CAPSULE is used to treat generalized anxiety disorders. It relieves anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.

Q: What precautions should I need to follow while taking LYRICA 150MG CAPSULE?

A: Before taking LYRICA 150MG CAPSULE inform your doctor if you have or had any lung, liver, kidney or heart problems. You must also inform your doctor before taking LYRICA 150MG CAPSULE if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse. Avoid consuming alcohol while taking LYRICA 150MG CAPSULE. Do not take LYRICA 150MG CAPSULE if you are pregnant or breastfeeding without consulting your doctor. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE. Inform your doctor immediately if you experience extreme sadness with thought of harming or killing yourself (suicidal thoughts) after taking LYRICA 150MG CAPSULE.

Q: Can LYRICA 150MG CAPSULE be used in children?

A: LYRICA 150MG CAPSULE is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of clinical safety data. Therefore, consult your doctor for advice.

Q: Can LYRICA 150MG CAPSULE cause headache after taking it?

A: Yes. Headache is a common side effect of taking LYRICA 150MG CAPSULE. In case if you are experiencing a headache after taking LYRICA 150MG CAPSULE, try to rest and relax. Keep drinking plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol. Consult your doctor if headache persists for a long time.

REFERENCES

1. K.D. Tripathi. Antiepileptic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 420.

2. Charles P Taylor, Timothy Angelotti, Eric Fauman. Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. February 2007. [Accessed on 7th April 2022]. https://pubmed.ncbi.nlm.nih.gov/17126531/

3. Vivek Verma, Nirmal Singh, Amteshwar Singh Jaggi. Pregabalin in Neuropathic Pain: Evidence and Possible Mechanisms. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2014. [Accessed on 7th April 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915349/

4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 7th April 2022]. https://www.medicines.org.uk/emc/files/pil.7132.pdf

5. Parke Davis. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 7th April 2022]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/209501s000lbl.pdf

USEFUL DIAGNOSTIC TESTS

  • Nerve conduction test
  • Electroencephalogram (EEG)

AUTHOR DETAILS

Written By Srilekha. R, B.Pharm
Last updated on 27 Jan 2023 | 03:14 PM(IST)

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Pregabalin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    25 g
    Ingredient
    PREGABALIN 150MG
    Hsn Code
    30049043
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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