LYRICA 150MG CAPSULE contains Pregabalin which belongs to the group of medicines called Anticonvulsants. It is used in adults to treat neuropathic pain. Neuropathic pain (also known as nerve pain) is a long-lasting pain caused due to damage of nerves fibers present in the body. It is characterized by hot, burning, sharp, shooting, throbbing or stabbing pain sensations with tingling or numbness of body parts. It may also cause mood changes, sleep disturbances and tiredness if nerve fibers supplying the brain are damaged.
LYRICA 150MG CAPSULE can also be used to treat certain forms of epilepsy (fits or seizures) when used in combination with other anti-epileptic medicines. It may also be effective in treating generalized anxiety disorders (severe anxiety that affects daily activities) when other medicines are not effective.
Pregabalin controls seizure (fits) by reducing the abnormal activity of the nerve cells in the brain. It also reduces the pain by blocking the transmission of pain signals across the nervous system. It relieves anxiety by reducing the release of certain brain chemicals that causes abnormal mood stimulation and anxiety.
Before taking LYRICA 150MG CAPSULE inform your doctor if you have or had any lung, liver, kidney or heart problems. You must also inform your doctor before taking LYRICA 150MG CAPSULE if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse.
Avoid consuming alcohol while taking LYRICA 150MG CAPSULE as it may make you feel dizzier which can eventually lead to increased risk of injuries, falls or accidents. Do not take LYRICA 150MG CAPSULE if you are pregnant or breastfeeding without consulting your doctor. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE.
LYRICA 150MG CAPSULE should be used with extreme caution in elderly patients (aged above 65 years) particularly in those who have kidney problems. LYRICA 150MG CAPSULE may alter your blood sugar levels, therefore regularly check your blood sugar levels as a precaution. It may also cause weight gain in patients, particularly in those who are diabetic. If it bothers you, consult your doctor for advice.
Other most common side effects of taking LYRICA 150MG CAPSULE are dizziness, drowsiness, headache, dry mouth, blurred vision and swelling of body parts. Contact your doctor if any of these side effect worsens. Also, inform your doctor immediately if you experience extreme sadness with thought of harming or killing yourself (suicidal thoughts).
It is used in adults to treat:
LYRICA 150MG CAPSULE controls seizures by reducing the abnormal activity of the nerve cells in the brain. It acts as a specific analgesic for peripheral and central neuropathic pain by blocking the transmission of pain signals across the nervous system. It relieves anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.
Take LYRICA 150MG CAPSULE as advised by your physician. Swallow LYRICA 150MG CAPSULE with a glass of water. Do not crush or chew the medicine. LYRICA 150MG CAPSULE can be taken with or without food.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking LYRICA 150MG CAPSULE without consulting your doctor.
Stop taking LYRICA 150MG CAPSULE and consult your doctor immediately if you experience any of the following side effects:
Eat plenty of fiber rich foods such as fresh fruits, vegetables and cereals. Drink plenty of fluids. Exercise more regularly. Consult your doctor if this side effect bothers you.
Try to rest and relax. Get enough sleep. Avoid driving or operating any heavy tools or machines completely while you are feeling dizzy or drowsy. Do not consume excessive alcohol. Consult your doctor if your dizziness worsens.
Rest and relax. Keep yourself hydrated by drinking plenty of fluids such as water or electrolytes. Applying a pain-relieving balm on your forehead can be beneficial. Do not consume excessive alcohol, as it could aggravate your headache. Consult your doctor if your headache worsens.
Take LYRICA 150MG CAPSULE with or just after meals. Stick to simple meals. Avoid eating oil rich or spicy foods. Consult your doctor if your nausea worsens.
LYRICA 150MG CAPSULE is generally not recommended for use in pregnant women unless considered necessary by the physician. Therefore, consult your doctor before taking it. Women of childbearing age must use a suitable contraceptive method (non-hormonal methods) to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE.
LYRICA 150MG CAPSULE is not recommended for use in breastfeeding women unless considered necessary by the physician. Therefore, consult your doctor before taking it.
Do not drive or operate any heavy tools or machines if you feel dizzy or sleepy after taking LYRICA 150MG CAPSULE.
Avoid consumption of alcohol while taking LYRICA 150MG CAPSULE as it could increase your dizziness.
LYRICA 150MG CAPSULE should be used with caution in patients with kidney diseases (such as decreased urination). Therefore, consult your doctor before taking it.
LYRICA 150MG CAPSULE should be used with caution in patients with severe liver diseases. Therefore, consult your doctor before taking it.
Do not take LYRICA 150MG CAPSULE if you are allergic to the Pregabalin.
LYRICA 150MG CAPSULE should be used with caution in patients having respiratory problems. Therefore, consult your doctor before taking it.
LYRICA 150MG CAPSULE should be used with caution in patients who have a history of heart disease (Ex. high or low blood pressure). Therefore, consult your doctor before taking it.
Before taking LYRICA 150MG CAPSULE, inform your doctor if you:
Use in Pediatrics:
LYRICA 150MG CAPSULE is generally not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor before taking it.
Use in Geriatrics:
LYRICA 150MG CAPSULE should be used with caution in elderly patients (aged above 65 years). Therefore, consult your doctor before taking it. Proper dose adjustments and careful monitoring are required in such patients.
A. Drug – Drug interactions:
Before taking LYRICA 150MG CAPSULE, inform your doctor if you are taking any of the following medicines such as:
Overdosage:
If you or anyone else accidentally took more LYRICA 150MG CAPSULE, consult your doctor immediately or visit the nearby hospital straight away. Symptoms of overdosage might include feeling sleepy, confused, agitated or restless and fits.
Drug | : | Pregabalin |
Pharmacological Category | : | GABA analogs |
Therapeutic Indication | : | Neuropathic pain, Epilepsy, Generalised Anxiety Disorders |
Dosage Forms | : | Tablet, Capsule, Injection, Suspension |
Q: What is LYRICA 150MG CAPSULE used for?
A: LYRICA 150MG CAPSULE is an anticonvulsant drug with pain relieving properties. It is used in adults to treat neuropathic pain, certain forms of epilepsy (fits) and generalized anxiety disorders.
Q: What if I forget to take a dose of LYRICA 150MG CAPSULE?
A: If your forgot to take a dose of LYRICA 150MG CAPSULE, take it as soon as you remember. However, if it is time to take the next dose of LYRICA 150MG CAPSULE, skip the missed one and take the next dose at regular times. Do not take a double dose of LYRICA 150MG CAPSULE to compensate the missed dose.
Q: How long will it take for LYRICA 150MG CAPSULE to reduce nerve pain?
A: The time taken for LYRICA 150MG CAPSULE in treating your condition may vary from person-to-person depending upon the severity of the disease. But you may start noticing a difference from your condition after 2 weeks of using LYRICA 150MG CAPSULE. However, it may take several weeks for you to experience complete pain relief. Therefore, take LYRICA 150MG CAPSULE consistently as advised by your doctor. Do not skip doses or discontinue the therapy in the mid-way without consulting your doctor.
What happens if I stop taking LYRICA 150MG CAPSULE suddenly?
Do not stop taking LYRICA 150MG CAPSULE without consulting your doctor as it may precipitate unpleasant withdrawal symptoms (such as headache, difficulty in sleeping, nausea, anxiety, diarrhea, flu-like symptoms, convulsions, nervousness, depression, pain, sweating and dizziness). If you wish to stop LYRICA 150MG CAPSULE, talk to your doctor. Your doctor will gradually your daily dose of pregabalin and before complete cessation of therapy.
Q: Will taking a higher dose of LYRICA 150MG CAPSULE be more effective?
A: No. Do not take a higher dose of LYRICA 150MG CAPSULE than the prescribed one without consulting your doctor. Taking a higher dose of LYRICA 150MG CAPSULE may not be beneficial. Instead, it may cause serious side effects. If the prescribed dose is not effective for you, consult your doctor. Your doctor would prescribe a suitable higher dose for you or suggest an alternative therapy after evaluating your disease condition.
Q: Does LYRICA 150MG CAPSULE help with anxiety?
A: Yes. LYRICA 150MG CAPSULE is used to treat generalized anxiety disorders. It relieves anxiety by reducing the release of certain brain chemicals (GABA) that causes abnormal mood stimulation and anxiety.
Q: What precautions should I need to follow while taking LYRICA 150MG CAPSULE?
A: Before taking LYRICA 150MG CAPSULE inform your doctor if you have or had any lung, liver, kidney or heart problems. You must also inform your doctor before taking LYRICA 150MG CAPSULE if you have diabetes, any other nerve or brain disorders or if you have a history of drug abuse. Avoid consuming alcohol while taking LYRICA 150MG CAPSULE. Do not take LYRICA 150MG CAPSULE if you are pregnant or breastfeeding without consulting your doctor. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with LYRICA 150MG CAPSULE. Inform your doctor immediately if you experience extreme sadness with thought of harming or killing yourself (suicidal thoughts) after taking LYRICA 150MG CAPSULE.
Q: Can LYRICA 150MG CAPSULE be used in children?
A: LYRICA 150MG CAPSULE is generally not recommended for use in children and adolescents (under 18 years of age) due to lack of clinical safety data. Therefore, consult your doctor for advice.
Q: Can LYRICA 150MG CAPSULE cause headache after taking it?
A: Yes. Headache is a common side effect of taking LYRICA 150MG CAPSULE. In case if you are experiencing a headache after taking LYRICA 150MG CAPSULE, try to rest and relax. Keep drinking plenty of fluids such as water or electrolytes. Apply a pain-relieving balm on the forehead if needed. Do not consume too much of alcohol. Consult your doctor if headache persists for a long time.
1. K.D. Tripathi. Antiepileptic Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 420.
2. Charles P Taylor, Timothy Angelotti, Eric Fauman. Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. February 2007. [Accessed on 7th April 2022]. https://pubmed.ncbi.nlm.nih.gov/17126531/
3. Vivek Verma, Nirmal Singh, Amteshwar Singh Jaggi. Pregabalin in Neuropathic Pain: Evidence and Possible Mechanisms. NIH National Library of Medicine, National center for biotechnology information. Pubmed.gov. January 2014. [Accessed on 7th April 2022]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3915349/
4. Milpharm Limited. Electronic Medicines Compendium (EMC). [Revised in March 2022] [Accessed on 7th April 2022]. https://www.medicines.org.uk/emc/files/pil.7132.pdf
5. Parke Davis. U.S. Food & Drug Administration. [Revised in September 2017] [Accessed on 7th April 2022]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/209501s000lbl.pdf
Written By Srilekha. R, B.Pharm
Last updated on 27 Jan 2023 | 03:14 PM(IST)
Pregabalin CAPSULE : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage
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