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INTRODUCTION ABOUT AZENAS 500 TABLET

AZENAS 500 TABLET contains Azithromycin which belongs to the group of medicines called Macrolide antibiotics. It is used to treat mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis.

It is also used to treat ear infections and skin & soft tissue infections (such as an abscess/boil) in affected individuals which is also indicated for use to treat sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhoea) in affected individuals.

AZENAS 500 TABLET is not recommended for use in patients allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), and ketolides. It is also not recommended for use in patients with a history of cholestatic jaundice/hepatic dysfunction.

Before taking AZENAS 500 TABLET, inform your doctor if you have diabetes, myasthenia gravis (condition marked by weak muscles), heart problems, and/or kidney problems.

AZENAS 500 TABLET should be used with caution during pregnancy and in women planning for pregnancy only if it is clearly necessary. It is also advised to be used with caution in breast-feeding woman as it is unknown whether the medicine gets excreted in the breast milk.

AZENAS 500 TABLET is not recommended for use in children weighing less than 45 kgs which is advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor.

The most common side effects of taking AZENAS 500 TABLET are stomach cramps, nausea, vomiting, diarrhoea, flatulence, dizziness, headache, and/or skin rash. Consult your doctor if any of the symptoms worsen.

USES OF AZENAS 500 TABLET

  • Treats mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections (such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis)
  • Treats ear infections and skin & soft tissue infections (such as an abscess/boil) in affected individuals
  • Treats sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhea) in affected individuals

HOW AZENAS 500 TABLET WORKS

AZENAS 500 TABLET works by inhibiting bacterial protein synthesis (essential for the bacteria to growth) that results in its destruction thus preventing its growth and spread of infection in affected individuals.

DIRECTIONS FOR USE

Take AZENAS 500 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF AZENAS 500 TABLET

COMMON

  • stomach cramps, nausea, vomiting, diarrhoea, flatulence
  • dizziness, headache
  • numbness/pickling sensation
  • loss of appetite, taste disturbance
  • visual disturbances, deafness
  • skin rash, itching
  • joint pain
  • tiredness, weakness

UNCOMMON

  • yeast infections of the mouth and vagina
  • allergic reactions of varying severity
  • increased skin sensitivity to sunlight
  • feeling nervous
  • reduced sense of touch or sensation
  • sleepiness/sleeplessness
  • poor hearing/ringing in the ears
  • racing heartbeat, chest pain
  • constipation, fever
  • signs of inflammation of the liver such as jaundice (yellowing of skin and whites of eyes), loss of appetite, dark urine
  • general loss of strength
  • swelling
  • general discomfort

RARE

  • vertigo (spinning head)
  • agitation

Stop taking AZENAS 500 TABLET and contact your doctor immediately if you experience any of the following side effects:

  • sudden wheeziness, difficulty in breathing, swelling of eyelids, face/lips, rash, and/or itching (affecting the whole body)
  • signs of serious bowel inflammation such as severe/prolonged diarrhoea
  • signs of severe allergic skin reactions such as rash (causing redness and flaking of skin), scratch marks, and/or cracked skin
  • rapid/irregular heartbeat
  • low blood pressure
  • angioedema (swelling underneath the skin)
  • signs of cholestatic jaundice/hepatic dysfunction such as yellowing of skin and whites of eyes, dark urine
  • dizziness, faint/ suffer from muscle weakness
  • serious skin reaction such as Stevens-Johnson Syndrome (associated with signs such as blistering of the skin, mouth, eyes and genitals), Toxic epidermal necrosis (associated with signs such as blistering of the skin), Drug reaction with eosinophilia and systemic symptoms (such as small, itchy red bumps), and/or Acute generalized exanthematous pustulosis skin (associated with signs such as skin eruption with rapid appearance of red skin studded with small pustules)

HOW TO MANAGE SIDE EFFECTS

Constipation

Try to eat high-fiber foods such as vegetables, cereals, fresh fruit, and drink plenty of water. Involve in regular exercise (going for a daily walk or run) and if this does not help, consult and inform your doctor for receiving alternate treatments for constipation.

Diarrhea

Drink plenty of water and stay hydrated. Try to avoid taking any medicine on your own to treat diarrhea. Consult your doctor and inform them if the symptom gets worse.

Headache

If AZENAS 500 TABLET causes headache, then take rest and drink plenty of fluids. Try to avoid drinking alcohol. Ask your doctor to recommend a painkiller. Headaches should usually go away after the first week of taking AZENAS 500 TABLET. If it lasts more than a week or severe, inform your doctor.

Nausea And Vomiting

Try to take AZENAS 500 TABLET with or just after a meal or a snack. Stick to simple meals. Avoid eating rich or spicy food. Consult your doctor if symptom gets worse.

WARNING & PRECAUTIONS

PREGNANCY
Monitoring required

AZENAS 500 TABLET should be used with caution during pregnancy and in woman planning for pregnancy only if it is clearly necessary. Consult your doctor before taking the medicine.

BREASTFEEDING
Consult your doctor

AZENAS 500 TABLET should be used with caution in breastfeeding woman as it is unknown whether the medicine is excreted in breastmilk. Consult your doctor before taking the medicine.

DRIVING AND USING MACHINES
Use with Caution

Do not drive or operate any machines if AZENAS 500 TABLET affects your ability to drive or operate any machines.

KIDNEY
Use with Caution

AZENAS 500 TABLET should be taken with caution in patients with kidney problems. Consult your doctor for advice before taking the medicine.

LIVER
Consult your doctor

AZENAS 500 TABLET is not recommended for use in patients with a history of cholestatic jaundice/hepatic dysfunction. It should be used with caution in patients with other liver problems. Consult your doctor before taking the medicine.

ALLERGY
Contraindicated

Do not take AZENAS 500 TABLET if you are allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), ketolides, and/or any other ingredients of this medicine.

HEART DISEASE
Use with Caution

AZENAS 500 TABLET should be taken with caution in patients with heart problems such as prolongation of QT interval, Torsades de pointes, and other proarrhythmic conditions. Consult your doctor before taking the medicine.

USE IN PEDIATRICS
Contraindicated

AZENAS 500 TABLET is not recommended for use in children weighing less than 45 kgs. Consult your doctor before taking the medicine.

USE IN GERIATRICS
Use with Caution

AZENAS 500 TABLET should be used with caution in elderly patients (aged above 65 years). Consult your doctor before taking.

OTHERS

Before taking AZENAS 500 TABLET, inform your doctor if you:

  • diabetes
  • myasthenia gravis (condition marked by weak muscles)
  • intolerance to certain sugars

INTERACTIONS

A. Drug-Drug interactions:

Before taking AZENAS 500 TABLET, inform your doctor if you are taking any of the following medicine:

  • ergotamine (medicine used to treat migraine)
  • warfarin (medicine used to prevent blood clots)
  • ciclosporin (used to prevent transplanted organ rejection)
  • antacids (used to treat indigestion) Ex. aluminium hydroxide, magnesium carbonate
  • digoxin (used to treat heart failure)
  • colchicine (used for gout and familial Mediterranean fever)
  • terfenadine (used for skin allergy)
  • hydroxychloroquine, chloroquine (medicines used to treat malaria)
  • efavirenz, nelfinavir (medicines used in the treatment of HIV)
  • fluconazole (used to treat fungal infection)

Overdosage:

If you or anyone else accidentally take too much of AZENAS 500 TABLET, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Azithromycin
Pharmacological Category :   Macrolide antibiotics
Therapeutic Indication :   Bacterial infections         
Dosage Forms :   Capsule, Tablet, Dispersible tablet, Syrup, Dry syrup, Suspension, Oral Suspension, Liquid, Injection, Infusion, Gel, Eye ointment, Eye drops

MORE INFORMATION

  • Keep AZENAS 500 TABLET out of reach of children
  • Store AZENAS 500 TABLET at room temperature

FAQs ABOUT AZENAS 500 TABLET

Q: What is AZENAS 500 TABLET used for?

A: AZENAS 500 TABLET is used to manage mild to moderate susceptible infections caused by bacteria and other micro-organisms which includes chest, throat, nasal infections (such as bronchitis, pneumonia, tonsillitis, sore throat and sinusitis). It is also used to manage ear infections and skin and soft tissue infections (such as an abscess/boil). It also manages sexually transmitted diseases such as cervicitis (caused by organisms such as Chlamydia trachomatis/ Neisseria gonorrhoea) in affected individuals.

Q: How AZENAS 500 TABLET works?

A: AZENAS 500 TABLET works by inhibiting bacterial protein synthesis (essential for the bacteria to growth) that results in its destruction thus preventing its growth and spread of infection in affected individuals.

Q: What are the most common side effects of taking AZENAS 500 TABLET?

A: The most common side effects of taking AZENAS 500 TABLET are stomach cramps, nausea, vomiting, diarrhoea, flatulence, dizziness, headache, and/or skin rash. Consult your doctor if any of the symptoms worsen.

Q: How to take AZENAS 500 TABLET?

A: Take AZENAS 500 TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

Q: Who should avoid taking AZENAS 500 TABLET?

A: AZENAS 500 TABLET is not recommended for use in patients allergic to azithromycin, other antibiotics such as erythromycin/clarithromycin (macrolides), and/or ketolides. It is also not recommended for use in patients suffering from liver diseases such as cholestatic jaundice or hepatic dysfunction.  

Q: Is AZENAS 500 TABLET available over the counter?

A: AZENAS 500 TABLET is usually available by prescription only. It is important to consult with a healthcare provider before starting treatment with AZENAS 500 TABLET.

Q: Can AZENAS 500 TABLET be taken with food?

A: AZENAS 500 TABLET can be taken with or without food. However, taking it with food may help reduce the risk of gastrointestinal side effects such as nausea and stomach upset.

Q: Can AZENAS 500 TABLET cause drowsiness?

A: Drowsiness is not a common side effect of AZENAS 500 TABLET. However, some individuals may experience dizziness or fatigue while taking the medication. If you experience any significant drowsiness or dizziness, avoid driving or operating machinery until you know how the medication affects you.

Q: Can AZENAS 500 TABLET be used for dental infections?

A: AZENAS 500 TABLET may be prescribed by a healthcare provider to treat certain dental infections caused by bacteria. However, the appropriateness of AZENAS 500 TABLET for dental infections should be determined by a healthcare provider based on the specific circumstances of the infection.

Q: Can AZENAS 500 TABLET be used to manage viral infections such as the common cold or flu?

A: No. AZENAS 500 TABLET belongs to antibiotics and are only effective against bacterial infections. They will not work for viral infections such as the common cold or flu.

REFERENCES

1. KD Tripathi. Macrolide, Lincosamide, Glycopeptide and Other Antibacterial Antibiotics; Urinary Antiseptics. Essentials of Medical Pharmacology. Seventh edition. 2013. Page – 755.

2. Michael J Parnham , Vesna Erakovic Haber, Evangelos J Giamarellos-Bourboulis, Gianpaolo Perletti , Geert M Verleden, Robin Vos. Azithromycin: mechanisms of action and their relevance for clinical applications. NIH National Library of Medicine. National Center for Biotechnology Information. PubMed.gov.  August 2014. [Accessed on 6th October 2022] https://pubmed.ncbi.nlm.nih.gov/24631273/

3. John E Stupka, Eric M Mortensen, Antonio Anzueto, and Marcos I Restrepo. Community-acquired pneumonia in elderly patients. NIH National Library of Medicine. National Center for Biotechnology Information. PMC PubMed Central.  August 2010. [Accessed on 6th October 2022] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2917114/

4. Haupt Pharma Latina S.r.l. Electronic Medicines Compendium (EMC). [Revised in March 2022]. [Accessed 7th October 2022] https://www.medicines.org.uk/emc/files/pil.1073.pdf

5. Azilide. Micro Labs Ltd. [Accessed 7th October 2022] https://www.microlabsltd.com/elibrary/node/1984

6. Borg Pharmaceutical Ind. NEOZOLID 600 MG TABLETS. [Accessed 7th October 2022] https://www.borg-pharma.com/products/neozolid-600-mg-tablets/

7. Al-Rowad Pharmaceutical Industries. AZIROWA 1 GM FCT. [Accessed 7th October 2022] https://alrowadrpic.com/product/azirowa-1-gm-fct/

USEFUL DIAGNOSTIC TESTS

  • Complete blood count
  • Bacterial culture test

AUTHOR DETAILS

Written By Srilekha. R, B.Pharm
Last updated on 26 Feb 2024 | 10:44 AM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    10 g
    Ingredient
    Azithromycin 500 mg
    Hsn Code
    30042064
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