KEP X Syrup 100ml

INTRODUCTION

KEP X SYRUP is a combination of Bromhexine, Guaiphenesin and Terbutaline which belongs to the group of medicines called Mucolytics, Expectorant and Beta-agonist respectively. It is used in the treatment of productive cough when associated with bronchospasm in conditions such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema.

Bronchitis is an inflammation in the airway of the lungs which carry air to and from lungs. Chronic obstructive pulmonary disease (COPD) is a lung disease causing obstruction in the airway. Bronchiectasis is a condition where the airways of lungs become wide allowing the accumulation of mucus deposition making it prone to infections. Emphysema is a lung disease causing shortness of breath. KEP X SYRUP should be used with caution in patients with high blood pressure, heart diseases such as arrhythmias, coronary insufficiency, uncontrolled diabetes mellitus, low levels of serum potassium, peptic ulcer and patients with high levels of thyroid and seizures.

Safety of KEP X SYRUP has not been studied in pregnancy and lactation. Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it. The most common side effects of KEP X SYRUP are tremors, nervousness, headache, drowsiness, vomiting, nausea, sweating, muscle cramps, hypersensitivity, rash, shortness of breath, chest discomfort, weakness, anxiety, and dry mouth. Consult your doctor if any of the above side effects worsen or persists for a longer duration.

USES OF KEP X SYRUP

It is used to treat productive cough when associated with bronchospasm in conditions such as:

• bronchitis
• bronchial asthma
• chronic obstructive pulmonary disease (copd)
• bronchiectasis
• emphysema

HOW KEP X SYRUP WORKS

KEP X SYRUP is a combination of Bromhexine, Guaiphenesin and Terbutaline. Bromhexine liquifies thick, tenacious sputum. Viscosity of sputum is reduced by dissolving mucopolysaccharide fibres and also improves mucociliary clearance of secretions. Guaiphenesin increases the output of sputum and bronchial secretions by reducing adhesiveness and surface tension. By increasing the volume of bronchial secretions, it reduces the viscosity of tenacious sputum. Terbutaline is a directly acting sympathomimetic agent with selective b2 stimulant effect which helps to alleviate bronchospasm associated with cough.

DIRECTIONS FOR USE

Take KEP X SYRUP as advised by your physician. Shake well before use. Your doctor will decide the correct dose and duration for you depending upon your age, body weight and disease condition.

SIDE EFFECTS OF KEP X SYRUP

HOW TO MANAGE SIDE EFFECTS

Dizziness Or Drowsiness

Sit or lie down when you feel dizzy and rest until the dizziness goes away. This can prevent the possibility of losing your balance, avoid caffeine, alcohol, and tobacco, they may trigger dizziness or make it worse. Drink at least eight glass of water a day, get seven hours of sleep, and avoid stressful situations. Eat a healthful diet that consists of vegetables, fruits, and lean proteins to help prevent dizziness.

Nausea And Vomiting

Drink clear or ice-cold drinks. Eat light, bland foods. Avoid fried, greasy, or sweet foods. Eat slowly and eat smaller, more frequent meals, drinking gradually larger amounts of clear liquids, avoid solid food until the vomiting episode has passed, take rest. If the symptom does not improve, contact your doctor.

WARNING & PRECAUTIONS

PREGNANCY

Consult your doctor

Safety of KEP X SYRUP has not been studied in pregnant women. Consult your doctor before taking it.

BREASTFEEDING

Consult your doctor

Safety of KEP X SYRUP has not been studied in breastfeeding women. Consult your doctor before taking it.

ALLERGY

Contraindicated

Do not take KEP X SYRUP if you are allergic to Bromhexine, Guaiphenesin, and terbutaline or any other ingredients of this medicine.

HEART DISEASE

Use with Caution

KEP X SYRUP should be used with caution in patients with high blood pressure (hypertension), heart diseases such as arrhythmias and coronary insufficiency. Consult your doctor before taking it.

USE IN PEDIATRICS

Consult your doctor

Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it.

INTERACTIONS

A. Drug-Drug interactions:

Before taking KEP X SYRUP, inform your doctor if you are taking any of the following medicine:

• medicines used to treat inflammation (Ex. prednisolone)
• medicines used to treat breathing difficulty (Ex. caffeine, theobromine, aminophylline, theophylline)
• medicines used to treat fluid accumulation (Ex. furosemide)
• medicine used to treat severe allergic reactions (Ex. epinephrine)

Overdosage:

If you or anyone else accidentally took more of KEP X SYRUP, consult your doctor immediately or visit the nearby hospital. Symptoms of overdose low blood pressure (hypotension).

SYNOPSIS

MORE INFORMATION

• Keep KEP X SYRUP out of reach of children
• Store at room temperature

FAQs ABOUT KEP X SYRUP

Q: What is KEP X SYRUP used for?

A: KEP X SYRUP is used in the treatment of productive cough when associated with bronchospasm in conditions such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema.

Q: What does KEP X SYRUP do?

A: Bromhexine a mucolytic agent works by reducing the thickness of the sputum and promotes clearance of the secretions. Guaiphenesin is an Expectorant which promotes the sputum output. Terbutaline is a sympathomimetic agent which relives bronchospasm (narrowing of smooth muscle).

Q: What are the common side effects of KEP X SYRUP?

A: The most common side effects of KEP X SYRUP are tremor, nervousness, headache, drowsiness, vomiting, nausea, sweating, muscle cramps, hypersensitivity, rash, shortness of breath, chest discomfort, weakness, anxiety, and dry mouth.

Q: Can I take KEP X SYRUP for runny nose?

A: No,  KEP X SYRUP is intended to treat productive cough associated with lung diseases causing breathing difficulties such as bronchitis, bronchial asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, and emphysema Consult your doctor before taking it.

Q: Can I give KEP X SYRUP for my child?

A: Your doctor will prescribe the right dose depends on your child’s age, body weight and health condition. Consult your doctor before taking it.

Q: Can we use KEP X SYRUP during pregnancy and breastfeeding?

A: Safety of KEP X SYRUP has not been studied in pregnancy and lactation. Consult your doctor before taking the medicine.

REFERENCES

1. KD. Tripathi Drugs for cough and bronchial asthma Essentials of medical pharmacology. Seventh edition. 2013. page no -219, 223, 218-219.

2. Senthilraja M And Giriraj P, Reverse Phase HPLC Method For The Simultaneous Estimation Of Terbutanile Sulphate, Bromhexine HCL And Guaifenesin In Cough Syrup Asian Journal of Pharmaceutical and Clinical Research February 2011. [Accessed on 7th July 2022] https://www.researchgate.net/publication/286957596_Reverse_phase_hplc_method_for_the_simultaneous_estimation_of_terbutanile_sulphate_bromhexine_HCl_and_guaifenesin_in_cough_syrup

3. Pfizer Limited. [Revised in July 2021] [Accessed on 7th July 2022] https://labeling.pfizer.com/ShowLabeling.aspx?id=14815

4. Cachet Pharmaceuticals Pvt. Ltd U.S. Food & Drug Administration. [Accessed on 7th July 2022] https://fdaghana.gov.gh/img/smpc/Eascof-T%20Expectorant%20Liquid%20Oral%20Syrup%20(Bromhexine%20Hydrochloride,%20Terbutaline%20Sulphate%20and%20Guaifenesin).pdf

5. Torque pharmaceuticals. [Accessed on 7th July  2022] https://torex.co.in/product/torex-br-cough-syrup/

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 20 Mar 2023 | 02:53 PM(IST)