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INTRODUCTION

PERISET SYRUP contains Ondansetron which belongs to a group of medicines called Anti-emetics. PERISET SYRUP is used to prevent nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery.

Before giving PERISET SYRUP, to your child, inform your doctor if your child have or had severe constipation, heart problems, liver, kidney problems, imbalance with the levels of salts in your blood, (potassium, sodium, and magnesium), or have been scheduled for any surgery. During the therapy, your doctor would regularly monitor your child’s health to avoid the risk of side effects.

Your doctor will prescribe the right dose and duration depends on the child’s age, body weight and health condition, so stick to the dose, time, and duration prescribed by the doctor.  Minor and temporary side effects may be experienced after the intake of this medicine. These includes headache, flushing and constipation.

Generally, these effects subside once the child’s body adapts to the medicine. However, in case of prolonged or bothersome events, consult your doctor immediately without any delay. Inform your doctor about your child’s complete medical history including any previous episodes of allergies.

USES OF PERISET SYRUP

  • Used to prevent nausea and vomiting in children caused by cancer chemotherapy, radiation therapy, and surgery

HOW PERISET SYRUP WORKS

PERISET SYRUP is a serotonin 5-HT3 receptor antagonist (specific chemical receptor), and it works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

DIRECTIONS FOR USE

Always give this PERISET SYRUP to your child as instructed by your doctor. Shake well before use. It is for pediatric use. Your doctor will prescribe the right dose depends on your child’s age body weight and disease condition.

SIDE EFFECTS OF PERISET SYRUP

COMMON

  • headache
  • constipation
  • weakness
  • tiredness
  • chills and drowsiness

RARE

Stop giving PERISET SYRUP and contact your doctor immediately if your child experience any of the following side effects:      

  • severe allergic reaction which may include a red and lumpy skin rash (hives), difficulty with breathing, sudden wheezing, swelling of the face, mouth, lips or eyelids or a high temperature (fever)

HOW TO MANAGE SIDE EFFECTS

Headache:

Give plenty of water and apply a wet or cold cloth on child’s forehead. Apply pain balm to head to ease off the pain. If there is no improvement in the symptom, contact your doctor.

Constipation:

Give more fiber-rich foods like green leafy vegetables and fruits. Give lots of water. If there is no improvement in the symptom, contact your doctor.

WARNING & PRECAUTIONS

DRIVING AND USING MACHINES

Do not allow your child drive or play outdoors, as PERISET SYRUP may cause dizziness or blurry vision. Consult your doctor before giving PERISET SYRUP.

KIDNEY

PERISET SYRUP should be used with caution if the child has kidney disease. Consult your doctor before giving PERISET SYRUP.

LIVER

PERISET SYRUP should be used with caution if the child has liver disease. Consult your doctor before giving PERISET SYRUP.

ALLERGY

Do not use PERISET SYRUP if your child is allergic (hypersensitive) to Ondansetron or any other ingredients of this medicine.

HEART DISEASE

PERISET SYRUP should be used with caution if your child has any heart disease. If needed, dose will be adjusted accordingly. Consult your doctor for advice.

OTHERS

Before giving PERISET SYRUP, inform your doctor if your child had or have:

  • problems with the levels of salts in the blood, such as potassium, sodium, and magnesium
  • severe constipation or gut problems like blockage
  • are intolerant to some sugars (Ex. fructose intolerance)

Use in pediatrics:

Your doctor will prescribe the right dose and frequency depends on your child’s age, body weight and disease condition. Consult your doctor before giving PERISET SYRUP.

INTERACTIONS

A. Drug-Drug Interactions:

Before using PERISET SYRUP, inform your doctor if your child is taking any of the following medicine:

  • medicines used to treat fits/epilepsy (ex. phenytoin, carbamazepine)
  • medicines used to treat lung infections (ex. rifampicin)
  • tramadol (used to treat severe pain)
  • medicines used to treat heart problems such as abnormal heart beats (anti-arrhythmic   ex. amiodarone)  
  • cancer medicines (ex. doxorubicin, daunorubicin and monoclonal, trastuzumab) 
  • medicines used to treat infections (erythromycin, ketoconazole)

Overdosage:

If your child accidentally takes too much of PERISET SYRUP, consult your doctor immediately or visit the nearby hospital.

SYNOPSIS

Drug :   Ondansetron
Pharmacological Category :   Serotonin antagonist
Therapeutic Indication :   Nausea and Vomiting in patients (undergoing chemotherapy, radiotherapy, surgery)
Dosage Forms :   Tablet, Injection, Dispersible Tablet, Syrup, Suspension, Oral strips, Lozenges, Pastille

MORE INFORMATION

  • Keep the medicine out of reach in children
  • Store PERISET SYRUP at room temperature

FAQs ABOUT PERISET SYRUP

Q: What PERISET SYRUP is used for?

A: PERISET SYRUP is generally given before any major surgery or before chemotherapy and radiotherapy sessions. In case your child is about to undergo any of the above procedures, the doctor may ask you to give PERISET SYRUP to your child to prevent vomiting post-procedure.

Q: What if my child takes too much PERISET SYRUP?

A: PERISET SYRUP is unlikely to cause harm if you give an extra dose by mistake. However, you must still tell your child’s doctor immediately.

Q: Can other medicines be given at the same time as PERISET SYRUP?

A: PERISET SYRUP may interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting PERISET SYRUP. Also, check with your child’s doctor before giving any medicine to your child.

Q: For how long should I give PERISET SYRUP?

A: Your doctor might advise you on how long your child should continue to take PERISET SYRUP. You will need to consult your doctor from time to time to review the child’s treatment and assess the symptoms.

Q: What are the side effects are seen with PERISET SYRUP?

A: The most common side effects include PERISET SYRUP are headache, flushing (feeling of warmth), constipation. Consult your doctor if the above side effects persist for a long time.

REFERENCES

1. KD. Tripathi. Section 11, Gastrointestinal Drugs. Essentials of medical pharmacology. Seventh edition. 2013. Page – 661.

2. Alexandria Griddine, Jeffery S. Bush. Ondansetron Book from Stat Pearls Publishing, Treasure Island (FL), 16 May 2018 PMID: 29763014. [Revised on September 2021] [Accessed on 21st June 2022] https://europepmc.org/article/nbk/nbk499839

3. Apollo Pharma Ltd, Unit 1, Irwell Works, Lower Woodhill Road, Bury, BL8 1AA, UK, PL 14308/0015 [ Revised on June 20] [Accessed on 21st June 20221] https://www.medicines.org.uk/emc/files/pil.6049.pdf

4. Leeford. [Accessed on 21st June 20221] https://www.leeford.in/product/145/vomishield-drops

AUTHOR DETAILS

Written By Dr. Janet.C, Pharm.D
Last updated on 21 Jan 2023 | 09:28 AM(IST)

PRODUCT DETAILS
    Net Qty
    1 N
    Shelf Life
    720 Days
    Item Weight
    40 g
    Ingredient
    Ondansetron 2 mg
    Hsn Code
    30049035
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DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.

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